PROTEIN EXPRESSION ANALYSES AT THE SINGLE CELL LEVEL

Protein Expression Analyses at the Single Cell Level

Protein Expression Analyses at the Single Cell Level

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uri ease paw gel for cats The central dogma of molecular biology explains how genetic information is converted into its end product, proteins, which are responsible for the phenotypic state of the cell.Along with the protein type, the phenotypic state depends on the protein copy number.Therefore, quantification of the protein expression in a single cell is critical for quantitative characterization of the phenotypic states.Protein expression is typically a dynamic and stochastic phenomenon that cannot be well described by standard experimental methods.

As an alternative, fluorescence imaging is being explored for the study of protein expression, because of its high sensitivity and high throughput.Here we review key recent progresses in fluorescence pet calming peanut butter imaging-based methods and discuss their application to proteome analysis at the single cell level.

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